ABSTRACT
Introduction: The tricuspid valve complex is present between the right atrium and right ventricle which consistsof i) Tricuspid orifice and its associated annulus ii) 3 Leaflets (anterior, septal, posterior); iii) 3 Commissures(anteroposterior, posteroseptal, anteroseptal); iv) 2 Papillary muscles (anterior, posterior, occasionally septal);v)Chordae tendinae of various types. Awareness of tricuspid valve complex is of great clinical importance incardiosurgery and is considered a prerequisite for successful, uncomplicated cardiac surgeries and interventionalradiology.Materials and Methods: 45 cadaveric human hearts have been utilized in this study. Conventional dissectiontechnique was performed and the detailed morphology of the tricuspid valve complex was studied. The followingobservations were taken a)Number of commissures b) Position of commissures c) Shape of orifice d) Number &shape of leaflets e) Presence or absence of accessory leaflets f) Position of normal and accessory leaflets, ifpresent, g) No. of scallops in posterior leaflet.Observations and results: The tricuspid orifice was elliptical in 34 hearts (75.6%) and triangular in 11 hearts(24.4%).The number of leaflets or cusps in the tricuspid valve complex showed variation. There were typical 3leaflets in 41 hearts (91.1%) with anterior, posterior and septal leaflets. In 4 hearts (8.9%) 4-cuspidal form wasnoticed with an accessory cusp. Three Commissures were identified between the leaflets in the 3-cuspidal form.They are anteroposterior, posteroseptal and anteroseptal.Conclusion: This knowledge of anatomical variation in the morphology of the tricuspid valve may help cardiacsurgeons during surgical procedures conducted for correction of valve defects
ABSTRACT
Context Oral squamous cell carcinoma (OSCC) has a multifactorial aetiology. Risk factors such as individual's lifestyle like chronic use of tobacco, spicy food, alcohol and smoking are associated with cancer. Recent studies have revealed the possibility of ABO blood group antigens role in development of cancer. Aims and objectives To detect and correlate ABO blood group type in oral potentially malignant disorders (OPMDs) and OSCC and to compare the ABO blood group type among controls, OPMDs and OSCC. Materials and methods Study included 100 subjects, 35 cases each of OPMDs and OSCC and 30 controls. ABO blood grouping was carried out by standard agglutination method (Spanclone ARKRAY Health Care Private Limited) based on the principle of haemagglutination reaction. Results We found that OPMDs and OSCC subjects to be more prevalent among cases with B blood group. There was a significant variation in age (P=0.004), sex (P=0.004) and blood group (P= 0.003) among controls, OPMDs and OSCC. Conclusion ABO blood grouping may be used as one of the diagnostic marker for OPMDs and OSCC.
ABSTRACT
Context Oral squamous cell carcinoma (OSCC) is one of the most common cancers in human population and has a multifactorial aetiology. It is often preceded by oral potentially Malignant Disorders (OPMDs). Studies have shown that OSCC and OPMDs cause significant variations in various haematological parameters. Aim and objectives To assess the role of haematological parameters like haemoglobin, erythrocyte sedimentation rate, red blood cell count, white blood cell count and differential leukocyte count in OPMDs and OSCC and also to compare these parameters among OPMDs, OSCC and controls. Materials and methods Study comprises 30 diagnosed cases each of OPMDs and OSCC and 10 normal healthy age and sex-related individuals. Blood sample was collected from the patients and was evaluated for various haematological parameters by Sahli's acid haematin method, Westergren method and Coulter Counter ZF-6. Results There was a statistically significant difference in haemoglobin, red blood cell count, erythrocyte sedimentation rate, differential leukocyte count between OSCC, OPMDs and controls. Conclusion In the present study, haematological parameters were significantly altered in OPMDs and OSCC, and these variations may be useful in the prediction of malignant transformation and prognosis.